The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A2and suppress PGE2formation in mesangial cells
Author:
Affiliation:
1. Institut für Pharmakologie; Universität Bern; Bern; Switzerland
2. Department of Biology; NTNU; University of Trondheim; Trondheim; Norway
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1476-5381.2012.02114.x/fullpdf
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3. Inhibition of Ca2+-independent phospholipase A2 by bromoenol lactone attenuates prostaglandin generation induced by interleukin-1 beta and dibutyryl cAMP in rat mesangial cells;Akiba;FEBS Lett,1998
4. Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-alpha- and interleukin-1beta-induced NF-kappa B activation;Anthonsen;J Biol Chem,2001
5. Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion;Bagga;Proc Natl Acad Sci USA,2003
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