Dependence of Apatite Formation on Silica Gel on Its Structure: Effect of Heat Treatment

Author:

Cho Sung‐Baek,Nakanishi Kazuki,Kokubo Tadashi,Soga Naohiro,Ohtsuki Chikara,Nakamura Takashi,Kitsugi Toshiaki,Yamamuro Takao

Abstract

The prerequisite for glasses and glass‐ceramics to bond to living bone is the formation of biologically active bonelike apatite on their surfaces in the body. Our previous study showed that a silica gel prepared by hydrolysis and polycon‐ densation of tetraethoxysilane in aqueous solution containing poly(ethy1ene glycol) induces apatite nucleation on its surface in a simulated body fluid. In the present study, the effects of heat treatment of silica gel on its catalytic effects in apatite nucleation was investigated in a simulated body fluid. I t was found that apatite forms on the surfaces of silica gels heat‐treated below 8OO°C, but not on those heat‐treated above 900°C. The volume of nanometer‐range pores in the gel remarkably decreased by heat treatment above 900°C. The concentration of silanol groups in the silica gels gradually decreased with increasing heat treatment temperature. The rate of silica dissolution from the gel into the simulated body fluid decreased remarkably by heat treatment above 900°C. This suggested that a special type of silanol group which is formed by soaking the gel treated below 800°C into the simulated body fluid is respon sible for apatite nucleation.

Publisher

Wiley

Reference45 articles.

1. Bonding mechanisms at the interface of ceramic prosthetic materials

2. Glass Ceramic–‐A New Bioactive Implant Material;Blencke B. A.;Med.-Orthop. Tech.,1975

3. Apatite‐ and Wallastonite‐Containing Glass‐Ceramics for Prosthetic Application;Kokubo T.;Bull. Inst. Chem. Res., Kyoto Univ.,1982

4. Machinable Bioactive Glass Ceramic;Holand W.;Wiss. Z. Friedrich-Schiller-Univ. Jena, Math.-Naturwiss. Reihe.,1983

5. Model for Physical Properties and Bioactivity of Phosphate Opal Glasses;Anderson O. H.;Glastech. Ber.,1988

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.7亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2025 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3