Low <scp>NUDT15</scp> expression levels due to biallelic <scp> <i>NUDT15</i> </scp> variants and 6‐mercaptopurine intolerance-Reference-Cited by-同舟云学术

Low NUDT15 expression levels due to biallelic NUDT15 variants and 6‐mercaptopurine intolerance

Published:2022-07-29 Issue:2 Volume:199 Page:270-276
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Yoshida Masanori¹^ORCID,Brown Scott A.²,Moriyama Takaya³,Nishii Rina³,Tsujimoto Shin‐ichi¹,Yamada Yuji⁴,Yoshida Kaoru¹,Shirai Ryota¹,Osumi Tomoo¹⁴^ORCID,Utano Tomoyuki⁵,Fukano Reiji⁶^ORCID,Kudo Ko⁷,Sakaguchi Kimiyoshi⁸^ORCID,Arakawa Yuki⁹,Koh Katsuyoshi⁹,Sekiguchi Masahiro¹⁰,Sekimizu Masahiro¹¹,Miyamura Takako¹²^ORCID,Ishida Hisashi¹³^ORCID,Inukai Takeshi¹⁴^ORCID,Tomizawa Daisuke⁴^ORCID,Kiyokawa Nobutaka¹,Kato Motohiro¹⁴¹⁰^ORCID,Yang Jun J.³¹⁵

Affiliation:

1. Department of Pediatric Hematology and Oncology Research Research Institute, National Center for Child Health and Development Tokyo Japan

2. Department of Immunology St. Jude Children's Research Hospital Memphis Tennessee USA

3. Department of Pharmacy and Pharmaceutical Sciences St. Jude Children's Research Hospital Memphis Tennessee USA

4. Children's Cancer Center National Center for Child Health and Development Tokyo Japan

5. Department of Pharmaceuticals National Center for Child Health and Development Tokyo Japan

6. Department of Pediatrics Yamaguchi University Graduate School of Medicine Ube Japan

7. Department of Pediatrics Hirosaki University Graduate School of Medicine Hirosaki Japan

8. Department of Pediatrics Hamamatsu University School of Medicine Hamamatsu Japan

9. Department of Hematology/Oncology Saitama Children's Medical Center Saitama Japan

10. Department of Pediatrics Graduate School of Medicine, the University of Tokyo Tokyo Japan

11. Department of Pediatrics National Hospital Organization Nagoya Medical Center Nagoya Japan

12. Department of Pediatrics Osaka University Graduate School of Medicine Suita Japan

13. Department of Pediatrics Okayama University Hospital Okayama Japan

14. Department of Pediatrics School of Medicine, University of Yamanashi Yamanashi Japan

15. Department of Oncology St. Jude Children's Research Hospital Memphis Tennessee USA

Funder

Japan Agency for Medical Research and Development

National Institutes of Health

St. Jude Children's Research Hospital

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.18375

Reference18 articles.

1. Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer

2. Treatment and biology of pediatric acute lymphoblastic leukemia

3. Systemic Exposure to Mercaptopurine as a Prognostic Factor in Acute Lymphocytic Leukemia in Children

4. Prognostic Importance of 6-Mercaptopurine Dose Intensity in Acute Lymphoblastic Leukemia

5. Toxicity and response to thiopurines in patients with inflammatory bowel disease

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3. Screening for mercaptopurine intolerance inALL– target the genes or their product?;British Journal of Haematology;2022-09-19