MicroRNA-30a promotes extracellular matrix degradation in articular cartilageviadownregulation of Sox9

Author:

Chang Tingjie12,Xie Jie1,Li Hongzhuo2,Li Dong2,Liu Ping13,Hu Yihe1

Affiliation:

1. Department of Orthopedics; Xiangya Hospital of Central South University; Changsha Hunan 410008 China

2. Department of Orthopedics; Peace Hospital of Changzhi Medical College; Changzhi Shanxi 046000 China

3. Department of oncology; Peace Hospital of Changzhi Medical College; Changzhi 046000 PR China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,General Medicine

Reference33 articles.

1. The role of the chondrocyte in osteoarthritis;Goldring;Arthritis Rheumatol.,2000

2. Cell death in cartilage;Kuhn;Osteoarthritis Cartilage,2004

3. Cytokines in cartilage injury and repair;Lotz;Clin. Orthop. Relat. Res.,2001

4. Update on the biology of the chondrocyte and new approaches to treating cartilage diseases;Goldring;Best Pract. Res. Clin. Rheumatol.,2006

5. Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases;Troeberg;FASEB J.,2008

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