Lactoferrin‐derived chimeric peptide (<scp>LFch</scp>) strongly boosts<scp>TGFβ1</scp>‐mediated inducible Treg differentiation possibly through downregulating<scp>TCR</scp>/<scp>CD28</scp>signalling-Reference-Cited by-同舟云学术

Lactoferrin‐derived chimeric peptide (LFch) strongly boostsTGFβ1‐mediated inducible Treg differentiation possibly through downregulatingTCR/CD28signalling

Published:2022-08-30 Issue:1 Volume:168 Page:110-119
ISSN:0019-2805
Container-title:Immunology
language:en
Short-container-title:Immunology

Author:

Jang Young‐Saeng¹²^ORCID,Yang Seok‐Won¹,Kim Tae‐Gyu¹,Song Ha‐Eon¹,Park Sunhee¹,Lee Eun Hye¹,Kang Seung‐Goo³,Yoon Sung‐il³,Ko Hyun‐Jeong⁴,Lee Geun‐Shik⁵,Park Seok‐Rae⁶,Seo Su Ryeon¹,Kim Pyeung‐Hyeun¹²

Affiliation:

1. Department of Molecular Bioscience, College of Biomedical Science Kangwon National University Chuncheon Republic of Korea

2. Institute of Bioscience and Biotechnology, Kangwon National University Chuncheon Republic of Korea

3. Division of Biomedical Convergence, College of Biomedical Science Kangwon National University Chuncheon Republic of Korea

4. College of Pharmacy Kangwon National University Chuncheon Republic of Korea

5. College of Veterinary Medicine Kangwon National University Chuncheon Republic of Korea

6. Department of Microbiology Konyang University College of Medicine Daejeon Republic of Korea

Funder

National Research Foundation of Korea

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/imm.13566

Reference24 articles.

1. Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells.

2. Induction of IL‐4‐producing CD4+ T cells by antigenic peptides altered for TCR binding;Tao X;J Immunol,1997

3. Low-strength T-cell activation promotes Th17 responses

4. IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation

5. CD40–CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

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1. Combined Treatment With TGF-β1, Retinoic Acid, and Lactoferrin Robustly Generate Inducible Tregs (iTregs) Against High Affinity Ligand;Immune Network;2023