Why Have So Many Drugs with Stellar Results in Laboratory Stroke Models Failed in Clinical Trials?
Author:
Publisher
Wiley
Subject
History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1749-6632.2003.tb07512.x/fullpdf
Reference23 articles.
1. Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing;Keyser;Trends Neurosci.,1999
2. Current status and perspectives of neuroprotection in ischemic stroke treatment;Martinez-Vila;Cerebrovasc. Dis.,2001
3. Clomethiazole acute stroke study in ischemic stroke (CLASS I) final results;Lyden;Stroke,2002
4. Lubelazole in acute ischaemic stroke treatment;Diener;A double-blind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubelazole with placebo. Stroke,2000
5. Tolerability of the low-affinity, use-dependent NMDA antagonist AR-R 15896 AR in stroke patients;Lees;A dose-ranging study. Stroke,2001
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