Noninvasive fetal genotyping of paternally inherited alleles using targeted massively parallel sequencing in parentage testing cases

Author:

Yang Donggui1,Liang Hao1,Gao Yu2,Lin Shaobin3,He Zhiming3,Gao Jun4,Sun Hongyu1,Li Qing5,Ma Xiaoyan5,Ou Xueling1

Affiliation:

1. Faculty of Forensic Medicine; Zhongshan School of Medicine, Sun Yat-sen University

2. Department of Obstetrics; The Sixth Affiliated Hospital of Sun Yat-sen University

3. Fetal Medicine Center, Department of Obstetrics and Gynecology

4. Reproductive Medicine Center; The First Affiliated Hospital of Sun Yat-sen University

5. Forensic Identification Institute of The Third Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes; Guangzhou P.R. China

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

Hematology,Immunology,Immunology and Allergy

Reference39 articles.

1. Presence of fetal DNA in maternal plasma and serum;Lo;Lancet,1997

2. Fetal DNA detection in maternal plasma throughout gestation;Galbiati;Hum Genet,2005

3. Rapid clearance of fetal DNA from maternal plasma;Lo;Am J Hum Genet,1999

4. Non invasive prenatal diagnosis of aneuploidy: next generation sequencing or fetal DNA enrichment?;Webb;Balkan J Med Genet,2012

5. Prenatal sex determination by DNA amplification from maternal peripheral blood;Lo;Lancet,1989

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