Characterization of a novel <i>IDH2</i>‐R159H mutation in acute myeloid leukaemia: Effects on cell metabolism and differentiation-Reference-Cited by-同舟云学术

Characterization of a novel IDH2‐R159H mutation in acute myeloid leukaemia: Effects on cell metabolism and differentiation

Published:2023-11-27 Issue: Volume: Page:
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Nardozza Anna Maria¹^ORCID,Guarnera Luca¹^ORCID,Travaglini Serena¹^ORCID,Ottone Tiziana¹²,Divona Mariadomenica¹³,De Bellis Eleonora⁴⁵,Savi Arianna⁶,Banella Cristina²,Noguera Nelida Ines¹²^ORCID,Di Fusco Davide⁷,Monteleone Ivan¹,Voso Maria Teresa¹²^ORCID

Affiliation:

1. Department of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy

2. Neuro‐Oncohematology Unit IRCCS Fondazione Santa Lucia Rome Italy

3. UniCamillus‐Saint Camillus International University of Health Sciences Rome Italy

4. Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology University of Rome Tor Vergata Rome Italy

5. SC Ematologia Azienda Sanitaria Universitaria Giuliano Isontina Trieste Italy

6. Department of clinical and biological sciences University of Turin Turin Italy

7. Department of Systems Medicine University of Rome Tor Vergata Rome Italy

Funder

Fondazione AIRC per la ricerca sul cancro ETS

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.19216

Reference15 articles.

1. Acute myeloid leukemia with IDH1 and IDH2 mutations: 2021 treatment algorithm

2. Isocitrate dehydrogenase mutations in myeloid malignancies

3. Isocitrate dehydrogenase variants in cancer — Cellular consequences and therapeutic opportunities

4. Tricarboxylic acid cycle dysfunction as a cause of human diseases and tumor formation

5. The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate