Detection of a latent soluble form of membrane type 1 matrix metalloprotease bound with tissue inhibitor of matrix metalloproteinases-2 in periprosthetic tissues and fluids from loose arthroplasty endoprostheses

Author:

Niarakis Anna1,Giannopoulou Eleftheria2,Ravazoula Panagiota3,Panagiotopoulos Elias4,Zarkadis Ioannis K.5,Aletras Alexios J.1

Affiliation:

1. Laboratory of Biochemistry; Department of Chemistry; University of Patras; Greece

2. Department of Pharmacology; School of Medicine; University of Patras; Greece

3. Department of Pathology; University Hospital of Patras; Greece

4. Department of Orthopaedics; School of Medicine; University of Patras; Greece

5. Department of Biology; School of Medicine; University of Patras; Greece

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference63 articles.

1. Aseptic loosening, not only a question of wear: a review of different theories;Sundfeldt;Acta Orthop,2006

2. Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies;Abu-Amer;Arthritis Res Ther,2007

3. Neutral proteinases and their inhibitors in the loosening of total hip prostheses;Takagi;Acta Orthop Scand Suppl,1996

4. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in joint fluid of the patients with loose artificial hip joints;Takei;J Biomed Mater Res,1999

5. Gelatinolytic and collagenolytic activity in periprosthetic tissues from loose hip endoprostheses;Syggelos;J Rheumatol,2001

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