Continuous monitoring is superior to manual measurements in detecting vital sign deviations in patients with COVID‐19

Author:

Grønbæk Katja Kjær1ORCID,Rasmussen Søren Møller2,Langer Natasha Hemicke1,Vincentz Mette3,Oxbøll Anne‐Britt1,Søgaard Marlene1,Awada Hussein Nasser3,Jensen Tomas O.45ORCID,Jensen Magnus Thorsten6,Sørensen Helge B. D.2,Aasvang Eske Kvanner37,Meyhoff Christian Sylvest17

Affiliation:

1. Department of Anaesthesia and Intensive Care Copenhagen University Hospital – Bispebjerg and Frederiksberg Copenhagen Denmark

2. Biomedical Signal Processing and AI Group, Digital Health Section, Department of Health Technology Technical University of Denmark Kgs. Lyngby Denmark

3. Department of Anesthesiology, Center for Cancer and Organ Disease Copenhagen University Hospital – Rigshospitalet Copenhagen Denmark

4. Department of Pulmonary and Infectious Diseases Copenhagen University Hospital – North Zealand Hospital Copenhagen Denmark

5. Center of Excellence for Health, Immunity, and Infections, Rigshospitalet University of Copenhagen Copenhagen Denmark

6. Department of Cardiology Copenhagen University Hospital Amager and Hvidovre Hospital Copenhagen Denmark

7. Department of Clinical Medicine University of Copenhagen Copenhagen Denmark

Abstract

AbstractBackgroundPatients admitted to the emergency care setting with COVID‐19‐infection can suffer from sudden clinical deterioration, but the extent of deviating vital signs in this group is still unclear. Wireless technology monitors patient vital signs continuously and might detect deviations earlier than intermittent measurements. The aim of this study was to determine frequency and duration of vital sign deviations using continuous monitoring compared to manual measurements. A secondary analysis was to compare deviations in patients admitted to ICU or having fatal outcome vs. those that were not.MethodsTwo wireless sensors continuously monitored (CM) respiratory rate (RR), heart rate (HR), and peripheral arterial oxygen saturation (SpO2). Frequency and duration of vital sign deviations were compared with point measurements performed by clinical staff according to regional guidelines, the National Early Warning Score (NEWS).ResultsSpO2 < 92% for more than 60 min was detected in 92% of the patients with CM vs. 40% with NEWS (p < .00001). RR > 24 breaths per minute for more than 5 min were detected in 70% with CM vs. 33% using NEWS (p = .0001). HR ≥ 111 for more than 60 min was seen in 51% with CM and 22% with NEWS (p = .0002). Patients admitted to ICU or having fatal outcome had longer durations of RR > 24 brpm (p = .01), RR > 21 brpm (p = .01), SpO2 < 80% (p = .01), and SpO2 < 85% (p = .02) compared to patients that were not.ConclusionEpisodes of desaturation and tachypnea in hospitalized patients with COVID‐19 infection are common and often not detected by routine measurements.

Funder

Innovationsfonden

Novo Nordisk Fonden

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine,General Medicine

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