SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions

Author:

Akiguchi Ichiro12ORCID,Pallàs Mercè3,Budka Herbert4,Akiyama Haruhiko5,Ueno Masaki6,Han Jingxian7,Yagi Hideo1,Nishikawa Tomohumi2,Chiba Yoichi6,Sugiyama Hiroshi8,Takahashi Ryoya9,Unno Keiko10,Higuchi Keiichi11,Hosokawa Masanori12

Affiliation:

1. Center of Neurological and Cerebrovascular Diseases, Koseikai Takeda Hospital; Kyoto Japan

2. Department of Health Science; Kyoto Koka Women's University; Kyoto Japan

3. Pharmacology Section and Institute of Neuroscience; University of Barcelona; Barcelona Spain

4. Institute of Neuropathology, University Hospital Zurich; Zurich Switzerland

5. Department of Clinical Research, Yokohama Brain and Spine Center; Yokohama Japan

6. Department of Pathology and Host Defence, Faculty of Medicine; Kagawa University; Takamatsu Japan

7. The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; Tianjin China

8. National Hospital Organization Utano Hospital; Kyoto Japan

9. Department of Biochemistry, Faculty of Pharmaceutical Sciences; Toho University; Chiba Japan

10. School of Pharmaceutical Sciences; University of Shizuoka; Shizuoka Japan

11. Department of Aging Biology; Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine; Matsumoto Japan

12. Institute for Developmental Research, Aichi Human Service Center; Nagoya Japan

Publisher

Wiley

Subject

Neurology (clinical),General Medicine,Pathology and Forensic Medicine

Reference89 articles.

1. Senescence-accelerated mouse (SAM): A novel murine model of accelerated senescence;Takeda;J Amer Geriatr Soc,1991

2. A novel murine model of aging, Senescence-Accelerated Mouse (SAM);Takeda;Arch Gerontol Geriatr,1994

3. Behavioral and neuropathological studies on strains of SAM with spontaneous age-related deficits in learning and memory;Takeda;Neuropathology,1991

4. Age-related changes in learning and memory in the senescence-accelerated mouse (SAM);Miyamoto;Physiol Behav,1986

5. Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal modal of disturbance in recent memory;Yagi;Brain Res,1988

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