Activation of melatonin receptor 2 but not melatonin receptor 1 mediates melatonin‐conferred cardioprotection against myocardial ischemia/reperfusion injury

Author:

Han Dong12ORCID,Wang Yongjun3,Chen Jiangwei12,Zhang Jibin2,Yu Peng2,Zhang Ran1,Li Shuang4,Tao Bo1,Wang Yabin1,Qiu Ya1,Xu Mengqi1,Gao Erhe5,Cao Feng12ORCID

Affiliation:

1. Department of Cardiology, National Clinical Research Center for Geriatric Diseases, 2nd Medical Center Chinese PLA General Hospital Beijing China

2. Department of Cardiology, Xijing Hospital Fourth Military Medical University Xi'an China

3. Department of Cardiovascular Surgery, Union Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan China

4. Department of Cardiology Chengdu Military General Hospital Chengdu China

5. Center for Translational Medicine Temple University School of Medicine Philadelphia Pennsylvania

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Endocrinology

Reference80 articles.

1. Heart disease and stroke statistics—2017 update: a report from the American Heart Association;Members WG;Circulation,2017

2. Targeting myocardial reperfusion injury—the search continues;Hausenloy DJ;N Engl J Med,2015

3. Evolving therapies for myocardial ischemia/reperfusion injury;Ibanez B;J Am Coll Cardiol,2015

4. Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways;Pandiperumal S;Prog Neurobiol,2008

5. Extrapineal melatonin: sources, regulation, and potential functions;Acuña‐Castroviejo D;Cell Mol Life Sci,2014

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