A retrospective analysis of 3954 patients in phase 2/3 trials of bortezomib for the treatment of multiple myeloma: towards providing a benchmark for the cardiac safety profile of proteasome inhibition in multiple myeloma

Author:

Laubach Jacob P.1ORCID,Moslehi Javid J.2,Francis Sanjeev A.3,San Miguel Jesús F.4,Sonneveld Pieter5,Orlowski Robert Z.6,Moreau Philippe7ORCID,Rosiñol Laura8,Faber Edward A.9,Voorhees Peter10,Mateos Maria-Victoria11,Marquez Loreta12,Feng Huaibao12,Desai Avinash13,van de Velde Helgi14,Elliott Jennifer14,Shi Hongliang14,Dow Edward15,Jobanputra Nishith14,Esseltine Dixie-Lee14,Niculescu Liviu14,Anderson Kenneth C.1,Lonial Sagar16,Richardson Paul G.1

Affiliation:

1. Dana-Farber Cancer Institute; Boston MA USA

2. Cardiovascular Division; Vanderbilt-Ingram Cancer Center; Cardio-Oncology Program; Vanderbilt University School of Medicine; Nashville TN USA

3. Formerly Cardio-Oncology Program; Massachusetts General Hospital; Boston MA USA

4. Clinica Universidad de Navarra; IDISNA; Centro Investigación Medica Aplicada (CIMA); Pamplona Spain

5. Department of Haematology; Erasmus Medical Centre; Rotterdam The Netherlands

6. Department of Lymphoma/Myeloma; The University of Texas M. D. Anderson Cancer Center; Houston TX USA

7. University Hospital Nantes; Nantes France

8. Hospital Clínic de Barcelona; IDIBAPS; Barcelona Spain

9. Oncology/Hematology Care; Cincinnati OH USA

10. Department of Hematologic Oncology and Blood Disorders; Levine Cancer Institute; Charlotte NC USA

11. Instituto de Investigación Biomédica de Salamanca; Instituto de Biología Molecular y Celular del Cáncer; Hospital Universitario Salamanca; Universidad de Salamanca-Consejo Superior de Investigaciones Cientificas; Salamanca Spain

12. Janssen Research & Development LLC; Raritan NJ USA

13. Janssen Global Services LLC; Raritan NJ USA

14. Millennium Pharmaceuticals Inc.; Cambridge MA USA

15. Foundation Medicine, Inc.; Cambridge MA USA

16. Winship Cancer Institute of Emory University; Atlanta GA USA

Funder

Millennium Pharmaceuticals Inc.

Janssen Global Services LLC

Publisher

Wiley

Subject

Hematology

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