Exposure to predator odor and resulting anxiety enhances the expression of the α2δ subunit of voltage-sensitive calcium channels in the amygdala

Author:

Nasca Carla1,Orlando Rosamaria1,Marchiafava Moreno1,Boldrini Paolo1,Battaglia Giuseppe2,Scaccianoce Sergio1,Matrisciano Francesco13,Pittaluga Anna4,Nicoletti Ferdinando12

Affiliation:

1. Department of Physiology and Pharmacology; University “Sapienza”; Roma Italy

2. I.R.C.C.S. Neuromed; Pozzilli Italy

3. The Psychiatric Institute; Department of Psychiatry; College of Medicine; The University of Illinois at Chicago; Chicago Illinois USA

4. Department of Experimental Medicine; Pharmacology and Toxicology Section; University of Genoa; Genoa Italy

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference46 articles.

1. Pregabalin and topiramate regulate behavioural and brain gene transcription changes induced by spontaneous cannabinoid withdrawal in mice;Aracil-Fernández;Addict. Biol.,2011

2. Auxiliary subunits: essential components of the voltage- gated calcium channel complex;Arikkath;Curr. Opin. Neurobiol.,2003

3. EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision;Attal;Eur. J. Neurol.,2010

4. Pregabalin for the treatment of generalized anxiety disorder: a novel pharmacologic intervention;Bandelow;Expert Rev. Neurother.,2007

5. The increased trafficking of the calcium channel Subunit α2δ1 into presynaptic terminals in neuropathic pain is inhibited by the α2δ ligand pregabalin;Bauer;J. Neurosci.,2009

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