An efficient, room temperature, oxygen radical anion (O2•−) mediated, one-pot, and multicomponent synthesis of spirooxindoles-Reference-Cited by-同舟云学术

An efficient, room temperature, oxygen radical anion (O2•−) mediated, one-pot, and multicomponent synthesis of spirooxindoles

Published:2017-12 Issue:12 Volume:95 Page:1296-1302
ISSN:0008-4042
Container-title:Canadian Journal of Chemistry
language:en
Short-container-title:Can. J. Chem.

Author:

Gajaganti Somaiah¹¹,Bajpai Shivam¹¹,Srivastava Vandana¹¹,Singh Sundaram¹¹

Affiliation:

1. Department of Chemistry, Indian Institute of Technology — BHU, Varanasi 221 005, Uttar Pradesh, India.

Abstract

The present report highlights an efficient use of oxygen radical anion to promote a room temperature multi-component synthesis of spirooxindoles (4a–4l) under mild reaction conditions. The potassium superoxide (KO2) and tetraethylammonium bromide (TEAB) combination generate the oxygen radical anion in situ to promote this transformation. This method offers a sustainable and direct access to the biologically important spirooxindole derivatives in good to excellent yields.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/cjc-2017-0432

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