Abstract
The hypoglycemic agents hypoglycin A and phenformin lower the ATP levels of slices of rat kidney and liver in vitro. These agents, as well as dinitrophenol, interfere with glucose production by kidney and liver slices in the presence of pyruvate or of various intermediate compounds of glycolysis. There is evidence that the activities of fructose-1,6-diphosphatase and glucose-6-phosphatase may be indirectly affected by these agents.
Publisher
Canadian Science Publishing
Cited by
40 articles.
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