The anesthetic potency of n-alcohols. A model spectroscopic study in inverted micelles

Abstract

A relation has been found between the anesthetic potency of n-alcohols (n = 1, 3, 6, 7, 9, 11, 14, and 16) and their association constants with polar groups in inverted micelles. From this point of view, cholesterol and 7-dehydrocholesterol behave like short-chain n-alcohols while cholestanol behaves like a long-chain n-alcohol.