Effects of dietary fiber content on energetics in nonreproductive and reproductive Brandt’s voles (Lasiopodomys brandtii)

Abstract

Food quality can affect many physiological characteristics in small mammals. Reproduction is a highly energy-demanding period especially for the females to produce and feed their offspring. We hypothesized that energy intake was constrained at different levels in nonreproductive and reproductive females and thus they adopted diverse energy strategies in response to diet changes. Here, we tested the effects of low fiber diet (3.5% vs. 12.4%) on energy intake and thermogenesis in nonreproductive and reproductive Brandt’s voles (Lasiopodomys brandtii (Radde, 1861)), a herbivorous species. We found that the voles decreased food intake while keeping a stable digestible energy intake (DEI) in response to the low fiber diet, but DEI was increased in reproductive voles at peak lactation. Uncoupling protein 1 content in brown adipose tissue decreased in nonreproductive voles, but was stable in reproductive voles on the low fiber diet. Litter mass on day 18 of age tended to increase in the low fiber group compared with that in the control group. Our findings demonstrate that the voles have a target intake to maintain energy balance when diet composition changes and energy intake may be constrained at a high level for the reproductive voles to improve their offspring’s fitness.