Krešimir Krnjević (1927–2021) and GABAergic inhibition: a lifetime dedication

Author:

Ben-Ari Yehezkel1,Cherubini Enrico2,Avoli Massimo3

Affiliation:

1. Neurochlore, Campus Scientifique de Luminy, 13288 Marseille Cedex 09, France.

2. European Brain Research Institute Rita Levi-Montalcini, 00161 Roma, Italy.

3. Montreal Neurological Institute-Hospital and Departments of Neurology & Neurosurgery and of Physiology, McGill University, Montreal, H3A 2B4 QC, Canada.

Abstract

After over seven decades of neuroscience research, it is now well established that γ-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain. In this paper dedicated to Krešimir Krnjević (1927–2021), a pioneer and leader in neuroscience, we briefly highlight the fundamental contributions he made in identifying GABA as an inhibitory neurotransmitter in the brain and our personal interactions with him. Of note, between 1972 and 1978 Dr. Krnjević was a highly reputed Chief Editor of the Canadian Journal of Physiology and Pharmacology.

Publisher

Canadian Science Publishing

Subject

Physiology (medical),Pharmacology,General Medicine,Physiology

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