1. Asper Clinical Research Institute, St. Boniface Hospital, Winnipeg, R2H 2A6 MB Canada
2. Department of Pharmacology and Therapeutics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, R3E 0T6 MB, Canada
3. Institute of Cardiovascular Sciences, Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, R3E 0J9 MB, Canada