Increased Spontaneous Apoptosis of CD4+CD25+T Cells in Patients with Active Rheumatoid Arthritis Is Reduced by Infliximab

Author:

TOUBI E.,KESSEL A.,MAHMUDOV Z.,HALLAS K.,ROZENBAUM M.,ROSNER I.

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference25 articles.

1. Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance;Sakaguchi;Immunol. Rev.,2001

2. CD4+ regulatory T cells in autoimmunity and allergy;Curotto de Lafaille;Curr. Opin. Immunol.,2002

3. Regulatory T cells in autoimmunity;Shevach;Annu. Rev. Immunol.,2000

4. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chain (CD25);Sakaguchi;Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol.,1995

5. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset;Sakaguchi;I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J. Exp. Med.,1985

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