CHRONOBIOLOGICAL ASPECTS OF SLEEP DISORDERS UNDER ANXIETY DISORDERS

Abstract

Modern research highlights the connection between the deterioration of sleep quality, sleep efficiency and daytime sleepiness with the disruption of the sleep-wake pattern due to circadian dysfunction. The aim of the study is to investigate the features of sleep disorders in patients with anxiety disorders of neurotic genesis, taking into account individual chronotype. 91 patients, 48 women (52,7%) and 43 men (47,3%) with anxiety disorders of neurotic origin were examined at Regional Center of Psychiatric Care. The Horn-Ostberg Morningness-Eveningness Questionnaire was used to determine the chronotype of participants. The study was also conducted using the Hamilton anxiety scale, Pittsburgh sleep quality questionnaire, Insomnia severity index, Epworth sleepiness scale, and Fatigue severity scale. All patients, depending on the individual chronotype, were divided into 3 groups, representative by age and gender. The morning type group comprised 32 patients (35.2%), the intermediate type group consisted of 31 patients (34.1%), and the evening type group included 28 patients (30.7%). A significant difference has been established between groups of morning and evening type in terms of the total score of anxiety and its somatic component (p<0.05). There is no difference in the indicator of the mental component of anxiety. However, this indicator is higher in people with extreme evening type compared to extreme morning type (p=0.001). Differences in indicators of sleep disturbances have been found to depend on the individual chronotype. Representatives of the evening type compared to the intermediate and morning types have significantly higher indicators of sleep latency and daytime dysfunction according to PSQI, as well as daytime sleepiness and fatigue severity (p<0.001). People with an intermediate chronotype have better sleep duration (p<0.05) and lower insomnia severity index than people with a morning (p<0.05) and evening type (p<0.01).