The RNA-binding protein PTBP1 promotes ATPase-dependent dissociation of the RNA helicase UPF1 to protect transcripts from nonsense-mediated mRNA decay

Author:

Fritz Sarah E.ORCID,Ranganathan Soumya,Wang Clara D.,Hogg J. RobertORCID

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference53 articles.

1. Nonsense-mediated mRNA decay: the challenge of telling right from wrong in a complex transcriptome;Kishor;Wiley Interdisciplinary Reviews: RNA,2019

2. Stress and the nonsense-mediated RNA decay pathway;Goetz;Cell. Mol. Life Sci,2017

3. Quality and quantity control of gene expression by nonsense-mediated mRNA decay;Kurosaki;Nat. Rev. Mol. Cell Biol,2019

4. UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond;Kim;RNA,2019

5. Purification and characterization of the Upf1 protein: a factor involved in translation and mRNA degradation;Czaplinski;RNA,1995

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