Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain-Reference-Cited by-同舟云学术

Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain

Published:2020-06 Issue:23 Volume:295 Page:7849-7864
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Richter Kirsten,Rufer Arne C.,Muller Magali,Burger Dominique,Casagrande Fabio,Grossenbacher Tabea,Huber Sylwia,Hug Melanie N.,Koldewey Philipp^ORCID,D'Osualdo Andrea,Schlatter Daniel,Stoll Theodor,Rudolph Markus G.^ORCID

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference61 articles.

1. ITAM-mediated signaling by the T-cell antigen receptor;Love;Cold Spring Harb. Perspect. Biol,2010

2. Selected signalling proteins recruited to the T-cell receptor-CD3 complex;Ngoenkam;Immunology,2018

3. Nck adapter proteins: functional versatility in T cells;Lettau;Cell Commun. Signal,2009

4. The adapter protein Nck: role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes;Lettau;Protein Sci,2010

5. Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation;Ngoenkam;Cell Commun. Signal,2014

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. SRC homology 3 domains: multifaceted binding modules;Trends in Biochemical Sciences;2022-09

2. Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli;Proceedings of the National Academy of Sciences;2022-08-17

3. New Label-Free Biosensing for the Evaluation of the AX-024 Inhibitor: Case Study for the Development of New Drugs in Autoimmune Diseases;Sensors;2022-02-05

4. Nck adaptors at a glance;Journal of Cell Science;2021-09-15

5. Sinner or Saint?: Nck Adaptor Proteins in Vascular Biology;Frontiers in Cell and Developmental Biology;2021-05-26