Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction

Author:

Luff Stephanie A.,Papoutsakis Eleftherios T.

Funder

National Science Foundation

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference82 articles.

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3. Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production;Panuganti;Tissue Eng. Part A,2013

4. Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes;Mostafa;Br. J. Haematol,2000

5. Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes;Shin;Proc. Natl. Acad. Sci. U.S.A,2011

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