Pediatric Gastrointestinal PEComas: A Diagnostic Challenge

Author:

Pizzi Marco1,di Lorenzo Ida2,d'Amore Emanuele S.3,D'Angelo Paolo4,Alaggio Rita1

Affiliation:

1. Department of Medicine-DIMED, General Pathology & Cytopathology Unit, University of Padova, Padova, Italy

2. Pathology Unit, ARNAS Civico, Di Cristina and Benfratelli Hospital, Palermo, Italy

3. Pathology Department, “San Bortolo” Hospital, Vicenza, Italy

4. Pediatric Hematology and Oncology Unit, ARNAS Civico, Di Cristina and Benfratelli Hospital, Palermo, Italy

Abstract

Perivascular epithelioid cell tumors (PEComas) in the pediatric population are very rare and frequently arise in the gastrointestinal tract. These tumors are characterized by variable morphological and immunohistochemical features, which may pose significant problems in differential diagnosis with other gastrointestinal mesenchymal tumors in pediatric patients. In presenting an unusual pediatric case of gastrointestinal PEComa, we also discuss the possible differential diagnosis of this rare entity.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology, and Child Health

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