Methods for real-time feature-guided image fusion of intrasurgical volumetric optical coherence tomography with digital microscopy

Author:

Trout Robert M.ORCID,Viehland Christian,Li Jianwei D.,Raynor William1,Dhalla Al-Hafeez,Vajzovic Lejla1,Kuo Anthony N.1,Toth Cynthia A.1,Izatt Joseph A.

Affiliation:

1. Duke University Medical Center

Abstract

4D-microscope-integrated optical coherence tomography (4D-MIOCT) is an emergent multimodal imaging technology in which live volumetric OCT (4D-OCT) is implemented in tandem with standard stereo color microscopy. 4D-OCT provides ophthalmic surgeons with many useful visual cues not available in standard microscopy; however it is challenging for the surgeon to effectively integrate cues from simultaneous-but-separate imaging in real-time. In this work, we demonstrate progress towards solving this challenge via the fusion of data from each modality guided by segmented 3D features. In this way, a more readily interpretable visualization that combines and registers important cues from both modalities is presented to the surgeon.

Funder

National Institutes of Health

Publisher

Optica Publishing Group

Subject

Atomic and Molecular Physics, and Optics,Biotechnology

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