Surgical microscope integrated MHz SS-OCT with live volumetric visualization

Author:

Britten AnjaORCID,Matten PhilippORCID,Weiss Jakob1,Niederleithner Michael,Roodaki Hessam2,Sorg Benjamin2,Hecker-Denschlag Nancy2,Drexler Wolfgang,Leitgeb Rainer A.,Schmoll Tilman3

Affiliation:

1. Technical University of Munich

2. Carl Zeiss Meditec AG

3. Carl Zeiss Meditec, Inc.

Abstract

Intraoperative optical coherence tomography is still not overly pervasive in routine ophthalmic surgery, despite evident clinical benefits. That is because today’s spectral-domain optical coherence tomography systems lack flexibility, acquisition speed, and imaging depth. We present to the best of our knowledge the most flexible swept-source optical coherence tomography (SS-OCT) engine coupled to an ophthalmic surgical microscope that operates at MHz A-scan rates. We use a MEMS tunable VCSEL to implement application-specific imaging modes, enabling diagnostic and documentary capture scans, live B-scan visualizations, and real-time 4D-OCT renderings. The technical design and implementation of the SS-OCT engine, as well as the reconstruction and rendering platform, are presented. All imaging modes are evaluated in surgical mock maneuvers using ex vivo bovine and porcine eye models. The applicability and limitations of MHz SS-OCT as a visualization tool for ophthalmic surgery are discussed.

Funder

Carl Zeiss Meditec AG

Publisher

Optica Publishing Group

Subject

Atomic and Molecular Physics, and Optics,Biotechnology

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