A Case Report of Worsening Alzheimer’s Disease Symptoms after COVID-19 Infection That Were Treated with Yigan-san-gami

Abstract

Introduction: In this case report, we describe the clinical effectiveness of Yigan-san-gami in improving symptoms in a patient with worsening Alzheimer’s dementia after COVID-19 infection.Case presentation: Symptoms of dementia worsened in a patient with Alzheimer’s disease after COVID-19 infection. Western medicines were added following neurological consultation. However, there was no medicinal effect. The patient was treated with Korean medicine (Yigan-san-gami) three times a day. We used daily charts, the Korean Mini-Mental State Examination-2 (K-MMSE-2), Clinical Dementia Rating (CDR), and Short Version Geriatric Depression Scale (SGDS) to assess the patient’s symptoms. Cognitive decline and behavioral and psychological symptoms of dementia (BPSD) improved following the treatment with Yigan-san-gami.Conclusion: The results suggest that Yigan-san-gami may be effective in improving symptoms of Alzheimer’s disease that worsen after COVID-19 infection.