FREQUENCY OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND ITS ASSOCIATION WITH DIABETES MELLITUS, HYPERTENSION AND CHOLELITHIASIS AMONG PATIENTS UNDERGOING ROUTINE ULTRASONOGRAPHY

Abstract

Objective: To find the frequency of non-alcoholic fatty liver disease (NAFLD) and its association with diabetes mellitus, hypertension and cholelithiasis. Methods: This was a cross-sectional study conducted in department of radiology, Sughra Shafi Medical Complex, Narowal. About 545 subjects who fulfilled the inclusion criteria were included through nonprobability/ convenient sampling technique. Abdominal ultrasound of every participant was conducted to determine frequency of NAFLD among sample size. A structured questionnaire consisting of demographic details and comorbidities was designed. Diabetic, and hypertensive status was determined on patient’s history and choleli-thiasis was assessed on ultrasonography. Data were entered in SPSS 21 software and presented as frequency and percentages. Results: Among 545 patients there were 282 (51.7%) male and 263 (48.3%) female participants with mean age of 48.56 ± 3.67 years SD. The overall frequency of NAFLD in the sample size was 39.8%. Diabetes was found in 115 (21.1%) participants, NAFLD was present in 44(64.7%) diabetic males and 29 (25.2%) diabetic females. Hypertension was found in 92 (16.9%) participants, NAFLD was present in 30(32.6%) hypertensive males and 24 (61.5%) hypertensive females. Cholelithiasis was found in 18 (8.0%) patients NAFLD was present in 30(32.6%) hypertensive males and 24 (61.5%) hypertensive females. There was no statistical significant difference among gender and presence of NAFLD. (P>0.05) Conclusion: It is concluded that on ultrasound NAFLD is a common finding and it is associated with diabetes mellitus, hypertension and cholelithiasis.