Atypical Presentation of Infantile Bullous Pemphigoid with Isolated C3 Deposits

Abstract

Bullous pemphigoid is an acquired autoimmune bullous disorder with autoantibodies targeting distinctive antigenic components of the skin and mucous membrane. It occurs mostly in the elderly, with the incidence of disease increasing with age and rare in children and infants. The clinical features are extremely polymorphous characterized by tense blisters and intense itching. The disease in pediatric population usually has a favorable outcome with appropriate treatment. Here, we present a case of infantile bullous pemphigoid with a rare presentation, triggered by vaccination and showing only linear C3 deposits.