Correlation of polypill and blood pressure level: A systematic review of clinical trials-Reference-Cited by-同舟云学术

Correlation of polypill and blood pressure level: A systematic review of clinical trials

Published:2023-05 Issue:1 Volume:12 Page:
ISSN:2277-9531
Container-title:Journal of Education and Health Promotion
language:en
Short-container-title:

Author:

Omrani Hamidreza¹,Bahremand Mostafa¹,Keshavarzi Fatemeh²,Solouki Leila²,Zereshki Ehsan¹

Affiliation:

1. Cardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

2. Student Research Committee, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran

Abstract

BACKGROUND: High blood pressure (BP) is considered as the most important risk factor for cardiovascular disease (CVD). The main aim of this study was to investigate the effect of polypill on BP by reviewing clinical trial studies. MATERIALS AND METHODS: In this systematic review study, online databases such as PubMed, Scopus, and Web of Science databases with no limited time were systematically searched until July 10, 2020. Clinical trial studies published in English that examined the effect of polypill on BP were included. BP was the main outcome investigated. RESULTS: Eleven original articles with a population of 17,042 people were reviewed. The polypill drugs studied in this study had different compounds. Compared to conventional care, treatment with polypill compounds has a positive and significant effect on lowering BP (P < 0.05). CONCLUSION: Our finding confirmed that polypills could reduce BP in patients. It seems that changing routine care and replacing it with a polypill strategy could facilitate the achievement of BP control goals.

Publisher

Medknow

Reference38 articles.

1. Cross-cultural adaptation and psychometric validation of the Persian version of the cardiac rehabilitation barriers scale (CRBS-P);Ghanbari-Firoozabadi;BMJ Open,2020

2. Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): A pragmatic, cluster-randomised trial;Roshandel;Lancet,2019

3. Future of polypill use for the prevention of cardiovascular disease and strokes;Chrysant;Am J Cardiol,2014

4. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: A systematic analysis for the global burden of disease study 2015;Lancet,2016

5. The effect of education based on health belief model on promoting preventive behaviors of hypertensive disease in staff of the Iran University of Medical Sciences;Azadi;Arch Public Health,2021