Clarification of Systemic Corticosteroid Therapy in Community-acquired Pneumonia

Author:

Hassanzad Maryam1ORCID,Asi Maedeh1,Valinejadi Ali2,Ghaffaripour Hosseinali1,Sadati Elham1,Derakhshan Korosh Fakhimi3,Velayati Ali Akbar4

Affiliation:

1. Pediatric Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Iran

2. Department of Health Information Technology, Khomein University of Medical Sciences, Khomein, Iran

3. Pediatric Disease Research Center, Guilan University of Medical Sciences, Rasht, Iran

4. Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

Abstract We received a complaint of fever and tachypnea from a 6-year-old girl who came to our hospital. She was treated for 20 days with antibiotics and corticosteroids. She was admitted for 10 days with a diagnosis of pneumonia and was discharged after the fever subsided. Two days after her discharge, the respiratory symptoms returned, and she came to us because of the severity of her symptoms. We diagnosed her with community-acquired pneumonia (CAP), performed the necessary radiographic and laboratory procedures, and the following outcomes were obtained: the computed tomography scan revealed consolidation between the right lung’s upper and middle lobes as well as an air bronchogram, but the chest ultrasound revealed no signs of pleural effusion. D-dimer, white blood cell, erythrocyte sedimentation rate, and C-reactive protein were also high in the laboratory test results, indicating pulmonary inflammation. She was finally diagnosed with CAP, and although the cause of the illness is unknown, she underwent a 14-day course of common antibiotics. Two days after the medication began, the fever subsided, and the tachypnea decreased. We believe that the corticosteroid treatment during the initial hospital stay is what caused the disease agent to persist and cause the fever to recur.

Publisher

Medknow

Reference7 articles.

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4. Recent advances in efficacy of corticosteroids as adjunct therapy for the treatment of community-acquired pneumonia in children: A systematic review and meta-analysis;Mukanhaire;MedRxiv,2022

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