A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis

Author:

Rakhee 1,Kumar Vivek2,Singh Chintu Kumar3,Arvind Ananya4,Ahsan Aasia5,Kumar Sudhanshu6,Das Debeswar7,Kumari Subham8

Affiliation:

1. Department of Oral Medicine and Radiology, Vananchal Dental College and Hospital, Garhwa, Jharkhand, India

2. Department of Oral and Maxillofacial Surgery, B.R. Ambedkar Institute of Dental Science and Hospital, Patna, Bihar, India

3. Department of Oral and Maxillofacial Pathology and Microbiology, Aditya Dental College and Hospital, Beed, India

4. IGIMS, Patna, Bihar, India

5. Department of Prosthodontics Crown and Bridge, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India

6. MDS, Oral Medicine and Radiology, Private Practice, Madhepura, Bihar, India

7. Oral Pathology and Microbiology and Forensic Odontology, Regional Dental College, Gwahati, India

8. BDS, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India

Abstract

ABSTRACT Aim: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS). Materials and Methods: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were randomly divided into two groups—the dexamethasone ointment group (Group I) and the triamcinolone acetonide gel group (Group II). Patients were asked to apply the gel three times a day on each ulcer. Estimation of the efficacy of gel was done based on the time required for regression in pain, size, and number of ulcers. Results: The results showed there was a significant difference in size, pain, number, and duration of ulcers in Group I and Group II within 7 days. However, in both groups, no significant difference was noted in the treatment of RAS. Conclusion: Dexamethasone ointment was found to be efficient in this treatment and was safe as evaluated using clinical assessments.

Publisher

Medknow

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,Bioengineering,General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,Bioengineering

Reference10 articles.

1. Recurrent aphthous stomatitis;Preeti;J Oral MaxillofacPathol,2011

2. Anevaluationof the efficacy of amlexanox and triamcinolone topical paste in the treatment of recurrent aphthousstomatitis;Chalkoo;International Journal of Contemporary MEDICAL Research,2018

3. Recurrent aphthous stomatitis;Porter;ClinDermatol,2000

4. Recurrent aphthous stomatitis;Ship;Oral Surg Oral Med Oral Pathol Oral RadiolEndod,1996

5. Recurrent aphthous stomatitis;Akintoye;Dent Clin North Am,2014

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