A comparative evaluation of adipokine VASPIN in female obese and non-obese subjects with periodontitis and health

Author:

Shilpa Akula1ORCID,Prasanna Jammula Surya1

Affiliation:

1. Department of Periodontics, Panineeya Institute of Dental Sciences and Research Centre, Kaloji Narayan Rao University of Health Sciences, Warangal, Telangana, India

Abstract

Introduction: Periodontitis and obesity are major health hazards. Adiposity stimulates cytokines which aggravate periodontitis. To balance this body secretes an anti-inflammatory adipokine-like visceral adipose tissue-derived serine protease inhibitor (VASPIN). Aims and Objectives: The study aimed to assess serum VASPIN levels in females with and without periodontitis, categorized by obesity status. Materials and Methods: Eighty female subjects with the age range of 35–44 years were included in this observational study. All have been categorized into four groups, 20 in each group. The division was based on the body mass index (BMI) and Russell's Periodontal Index (PI). Group I-with BMI 18.5–24.9 kg/m2; without PD (non-obese without PD) Group II-with BMI 25-29.9 kg/m2; with PD (non-obese with PD). Group III -with BMI ≥30 kg/m2; without PD (obese without PD).Group IV with BMI ≥30 kg/m2; with PD (Obese with PD). Statistics Used: Serum VASPIN levels were compared in all the groups. Among the groups were analyzed with ANOVA, Bartlett's test for homogeneity of variances, and Bonferroni test for multiple comparisons. Results: When VASPIN and BMI were correlated, higher levels were found in Group II, followed by Groups IV, III, and I. Serum VASPIN levels among the groups were statistically significant P < 0.0001. Conclusion: Serum VASPIN can be used for predicting the progression of periodontal inflammation associated with obesity and also can act as a good biomarker for the initial stages of obesity.

Publisher

Medknow

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3