Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis-Reference-Cited by-同舟云学术

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Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis

Published:2023-09 Issue: Volume:70 Page:100977
ISSN:1368-7646
Container-title:Drug Resistance Updates
language:en
Short-container-title:Drug Resistance Updates

Author:

Yu Jie^ORCID,Zhong Bingling,Zhao Lin,Hou Ying,Ai Nana,Lu Jin-Jian,Ge Wei,Chen Xiuping^ORCID

Funder

Universidade de Macau

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Wuhan Polytechnic University

Key Science and Technology Research Project in Jiangxi Province Department of Education

Natural Science Foundation of Hubei Province

Natural Science Foundation of Guangdong Province

Publisher

Elsevier BV

Subject

Pharmacology (medical),Infectious Diseases,Cancer Research,Pharmacology,Oncology

Reference34 articles.

1. NQO1: a target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms;Beaver;Biochim. Biophys. Acta Proteins Prote.,2019

2. NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues;Belinsky;Cancer Metastas. Rev.,1993

3. The metabolite alpha-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR;Chin;Nature,2014

4. A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker;Cho;Toxicol. Vitr.,2008

5. Phase 1 study of ARQ 761, a beta-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis;Gerber;Br. J. Cancer,2018

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