DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling
Author:
Funder
Chinese Academy of Sciences
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference47 articles.
1. Modulation of signaling through GPCR-cAMP-PKA pathways by PDE4 depends on stimulus intensity: possible implications for the pathogenesis of acrodysostosis without hormone resistance;Motte;Mol. Cell. Endocrinol.,2017
2. Evidence for a role of phosphodiesterase 4 in lipopolysaccharide-stimulated prostaglandin E2 production and matrix metalloproteinase-9 activity in human amniochorionic membranes;Oger;J. Immunol.,2005
3. Overexpression of phosphodiesterase-4 subtypes involved in surgery-induced neuroinflammation and cognitive dysfunction in mice;Wang;Brain Res. Bull.,2017
4. Increase of intracellular cyclic AMP by PDE4 inhibitors affects HepG2 cell cycle progression and survival;Massimi;J. Cell. Biochem.,2017
5. Advances in targeting cyclic nucleotide phosphodiesterases;Maurice;Nat. Rev. Drug Discovery,2014
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