Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients

Author:

Wickström Malin,Danielsson Katarina,Rickardson Linda,Gullbo Joachim,Nygren Peter,Isaksson Anders,Larsson Rolf,Lövborg Henrik

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference36 articles.

1. Disulfiram induces apoptosis in human melanoma cells: a redox-related process;Cen;Mol Cancer Ther,2002

2. Disulfiram-mediated inhibition of NF-kappaB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines;Wang;Int J Cancer,2003

3. Induction of apoptosis by thiuramdisulfides, the reactive metabolites of dithiocarbamates, through coordinative modulation of NFkappaB, c-fos/c-jun, and p53 proteins;Liu;Mol Carcinog,1998

4. Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease;Brar;Mol Cancer Ther,2004

5. Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis;Chen;Front Biosci,2005

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