Identification, characterization and biological studies of kinesine spindle protein inhibitor, benzo[b][1,4]oxazine-6-carboxamide derivative, via 3D-pharmacophore virtual screening-Reference-Cited by-同舟云学术

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Identification, characterization and biological studies of kinesine spindle protein inhibitor, benzo[b][1,4]oxazine-6-carboxamide derivative, via 3D-pharmacophore virtual screening

Published:2024-09 Issue: Volume:1312 Page:138508
ISSN:0022-2860
Container-title:Journal of Molecular Structure
language:en
Short-container-title:Journal of Molecular Structure

Author:

Elseginy Samia A.^ORCID

Funder

University of Bristol

Publisher

Elsevier BV

Reference63 articles.

1. Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone localization and sliding force;Gergely;Proc. Natl. Acad. Sci.,2023

2. Eg5 targeting agents: from new anti-mitotic based inhibitor discovery to cancer therapy and resistance;Garcia-Saez;Biochem. Pharmacol.,2021

3. Kinesin-5 Eg5 is essential for spindle assembly, chromosome stability and organogenesis in development;Yu;Cell Death Discov.,2022

4. Drug resistance dependent on allostery: a P-loop rigor Eg5 mutant exhibits resistance to allosteric inhibition by STLC;Indorato;Front. Oncol.,2022

5. Effective synthesis and biological evaluation of natural and designed bis(indolyl) methanes via taurine-catalyzed green approach;Chavan;ACS Omega,2022

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