Nuclear deformation regulates YAP dynamics in cancer associated fibroblasts

Author:

Emon BasharORCID,Joy M. Saddam H.ORCID,Lalonde LukeORCID,Ghrayeb AnanORCID,Doha UmniaORCID,Ladehoff LaurenORCID,Brockstein ReedORCID,Saengow Chaimongkol,Ewoldt Randy H.ORCID,Saif M. Taher A.

Funder

National Institutes of Health

National Institute of Biomedical Imaging and Bioengineering

Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign

National Science Foundation

Publisher

Elsevier BV

Subject

Molecular Biology,Biomedical Engineering,Biochemistry,Biomaterials,General Medicine,Biotechnology

Reference80 articles.

1. Mechanical Forces Matter in Health and Disease: From Cancer to Tissue Engineering;Vogel;Nanotechnology,2010

2. Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review;Emon;Comput Struct Biotechnol J,2018

3. Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated fibroblast-mediated prometastatic activin A signaling;Bauer;Sci Rep,2020

4. Substrate stiffness regulates proinflammatory mediator production through TLR4 activity in macrophages;Previtera;PLoS One,2015

5. Stromal fibroblasts in cancer initiation and progression;Bhowmick;Nature,2004

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