Increased Homer1-mGluR5 mediates chronic stress-induced depressive-like behaviors and glutamatergic dysregulation via activation of PERK-eIF2α-Reference-Cited by-同舟云学术

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Increased Homer1-mGluR5 mediates chronic stress-induced depressive-like behaviors and glutamatergic dysregulation via activation of PERK-eIF2α

Published:2019-12 Issue: Volume:95 Page:109682
ISSN:0278-5846
Container-title:Progress in Neuro-Psychopharmacology and Biological Psychiatry
language:en
Short-container-title:Progress in Neuro-Psychopharmacology and Biological Psychiatry

Author:

Li Ming-Xing,Li Qian,Sun Xue-Jiao,Luo Can,Li Yong,Wang Ya-Nan,Chen Jing,Gong Chen-Zi,Li Ya-Jie,Shi Li-Ping,Zheng Yi-Feng,Li Rong-Chun,Huang Xiao-Lin,Xiong Qiu-Ju,Chen Hong

Funder

Health and Family Planning Commission of Hubei Province

China Postdoctoral Science Foundation

Health and Family Planning Commission of Wuhan Municipality

National Natural Science Foundation of China

National Key Research and Development Program of China Stem Cell and Translational Research

Publisher

Elsevier BV

Subject

Biological Psychiatry,Pharmacology

Reference48 articles.

1. Calcium-dependent networks in dopamine-glutamate interaction: the role of postsynaptic scaffolding proteins;de Bartolomeis;Mol. Neurobiol.,2012

2. A Homer 1 gene variant influences brain structure and function, lithium effects on white matter, and antidepressant response in bipolar disorder: a multimodal genetic imaging study;Benedetti;Prog. Neuro-Psychopharmacol. Biol. Psychiatry,2018

3. Increased temporal cortex ER stress proteins in depressed subjects who died by suicide;Bown;Neuropsychopharmacology,2000

4. mGlu receptors as potential targets for novel antidepressants;Chaki;Curr. Opin. Pharmacol.,2018

5. Down-regulation of Homer1b/c attenuates glutamate-mediated excitotoxicity through endoplasmic reticulum and mitochondria pathways in rat cortical neurons;Chen;Free Radic. Biol. Med.,2012

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