Corydalis saxicola Bunting total alkaloids improve NAFLD by suppressing de novo lipogenesis through the AMPK-SREBP1 axis

Author:

Guo YatingORCID,Sun Qiushuang,Wang Shijiao,Zhang Mengdi,Lei Yuanyuan,Wu Jiejie,Wang Xinhong,Hu Wenjun,Meng Haitao,Li Zhiyu,Xu Luzhou,Huang Fang,Qiu Zhixia

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference43 articles.

1. De novo lipogenesis in health and disease;Ameer;Metabolism,2014

2. Lipogenesis inhibitors: therapeutic opportunities and challenges;Batchuluun;Nat. Rev. Drug Discov.,2022

3. Metabolic drivers of non-alcoholic fatty liver disease;Bence;Mol. Metabol.,2021

4. The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases;Chalasani;Hepatology,2018

5. Study on effect and molecular mechanism of Corydalis saxicola total alkaloids on nonalcoholic fatty liver mice;Chen;Drug Eval Res,2021

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