Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/alpha-synuclein signaling

Author:

Li Hong-Yan,Liu De-Shui,Li Li-Bo,Zhang Ying-Bo,Dong Hai-Ying,Rong Hua,Zhang Jing-Yan,Wang Jun-Ping,Jin Ming,Luo Nan,Zhang Xiao-Jie

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference52 articles.

1. TNF-α promotes α-synuclein propagation through stimulation of senescence-associated lysosomal exocytosis;Bae;Exp. Mol. Med.,2022

2. Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease;Brochard;J. Clin. Invest.,2009

3. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons;Bieri;Acta Neuropathol.,2019

4. Amentoflavone protects dopaminergic neurons in MPTP-induced Parkinson's disease model mice through PI3K/Akt and ERK signaling pathways;Cao;Toxicol. Appl. Pharmacol.,2017

5. Microbiome-gut-brain axis and toll-like receptors in Parkinson's disease;Caputi;Int. J. Mol. Sci.,2018

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