Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba Epimedii

Author:

Li Chenrui,Li Qiang,Mei Qibing,Lu Tingli

Funder

Fundamental Research Funds

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference170 articles.

1. Icariin stimulates MC3T3-E1 cell proliferation and differentiation through up-regulation of bone morphogenetic protein-2;Cao;Int. J. Mol. Med.,2012

2. Drug–drug interactions potential of icariin and its intestinal metabolites via inhibition of intestinal UDP-glucuronosyltransferases;Cao;Evid. Based Complement. Alternat. Med.,2012

3. Oral absorption and excretion of icaritin, an aglycone and also active metabolite of prenylflavonoids from the Chinese medicine Herba Epimedii in rats;Chang;Phytomedicine,2012

4. Icariin inhibits the osteoclast formation induced by RANKL and macrophage-colony stimulating factor in mouse bone marrow culture;Chen;Pharmazie,2007

5. Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells;Chen;Pharmazie,2005

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