Intrathecally injected tramadol reduces articular incapacitation and edema in a rat model of lipopolysaccharide (LPS)-induced reactive arthritis

Author:

Lucena Flora,Callado de Oliveira Débora M.M.,Norões Maíra M.,Mujica Elba M.M.,Melleu Fernando F.,Benedet Patrícia de O.,Stein Taciane,Ribeiro Lucineia F.C.,Tonussi Carlos R.ORCID

Funder

CAPES

CNPq

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference45 articles.

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2. Influence of tramadol on neurotransmitter systems of the rat brain;Frink;Arzneimittelforschung.,1996

3. Effects of the analgesic agent tramadol in normal and arthritic rats: comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine;Kayser;Eur. J. Pharmacol.,1991

4. What is the main mechanism of tramadol?;Minami;Naunyn Schmiedeberg’s Arch. Pharmacol.,2015

5. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an ‘atypical’ opioid analgesic;Raffa;J. Pharmacol. Exp. Ther.,1992

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