Adenosine diphosphate ribosylation factor 6 inhibition protects burn sepsis induced lung injury through preserving vascular integrity and suppressing ASC inflammasome transmission

Author:

Xiao MengjingORCID,Zhang Peirong,Chen Zimiao,Liu Xiaojie,Wei Wei,He Zhihao,Wang Yao,Cheng Jian,Zhu Zhen,Wen Jing,Yang HongmingORCID

Funder

Natural Science Foundation of Shenzhen Municipality

Science, Technology and Innovation Commission of Shenzhen Municipality

Publisher

Elsevier BV

Subject

Critical Care and Intensive Care Medicine,Emergency Medicine,General Medicine,Surgery

Reference34 articles.

1. Targeting the gut to prevent sepsis from a cutaneous burn;Adiliaghdam;JCI Insight,2020

2. Regulatory mechanisms, prophylaxis and treatment of vascular leakage following severe trauma and shock;Duan;Mil Med Res,2017

3. The systemic immune response to trauma: an overview of pathophysiology and treatment;Lord;Lancet,2014

4. Simvastatin treatment improves survival in a murine model of burn sepsis: role of interleukin 6;Beffa;Burns,2011

5. Oxidative stress and endothelial dysfunction in sepsis and acute inflammation;Joffre;Antioxid Redox Signal,2021

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