Glycan-Independent Gamete Recognition Triggers Egg Zinc Sparks and ZP2 Cleavage to Prevent Polyspermy

Author:

Tokuhiro Keizo,Dean Jurrien

Funder

National Institute of Diabetes and Digestive and Kidney Disease (NIDDK)

Uehara Memorial Foundation, Kanae Foundation for the Promotion of Medical Science

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Developmental Biology,Cell Biology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology

Reference70 articles.

1. Significance of egg's zona pellucida glycoproteins in sperm-egg interaction and fertilization;Abou-Haila;Minerva Ginecol.,2014

2. A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans;Avella;J. Cell Biol.,2014

3. ZP2 peptide-beads select human sperm in vitro, decoy mouse sperm in vivo, and provide reversible contraception;Avella;Sci. Transl. Med.,2016

4. The molecular basis of gamete recognition in mice and humans;Avella;Mol. Hum. Reprod.,2013

5. Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice;Baibakov;J. Cell Biol.,2012

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