Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial

Author:

Powles Thomas,van der Heijden Michiel S,Castellano Daniel,Galsky Matthew D,Loriot Yohann,Petrylak Daniel P,Ogawa Osamu,Park Se Hoon,Lee Jae-Lyun,De Giorgi Ugo,Bögemann Martin,Bamias Aristotelis,Eigl Bernhard J,Gurney Howard,Mukherjee Som D,Fradet Yves,Skoneczna Iwona,Tsiatas Marinos,Novikov Andrey,Suárez Cristina,Fay André P,Duran Ignacio,Necchi Andrea,Wildsmith Sophie,He Philip,Angra Natasha,Gupta Ashok K,Levin Wendy,Bellmunt Joaquim,Park Se Hoon,van der Heijden Michiel S.,Necchi Andrea,Castellano Daniel,Bamias Aristotelis,Lee Jae Lyun,De Giorgi Ugo,Bögemann Martin,Eigl Bernhard J.,Tsiatas Marinos,Powles Thomas,Novikov Andrey,Skoneczna Iwona,Mukherjee Som D.,Suarez Cristina,Westgeest Hans,Fradet Yves,Flechon Aude,Ou Yen-Chuan,Park Inkeun,Matveev Vsevolod,Pérez-Valderrama Begoña,Cheng Susanna,Frank Stephen,Gurney Howard,Anido Urbano,Hamzaj Alketa,Retz Margitta,Sridhar Srikala,Scagliotti Giorgio Vittorio,Voortman Jens,Alekseev Boris,Alyasova Anna,Komyakov Boris,Dumez Herlinde,Pavic Michel,Kimura Go,Mizokami Atsushi,Osanto Susanne,Arranz Jose Angel,Piersma Djura,Shin Sang Joon,Karyakin Oleg,Delgado Ignacio,Gonzalez Jose Luis,Pang See-Tong,Tran Anna,Lipatov Oleg,Su Wen-Pin,Flaig Thomas,Alva Ajjai,Park Kyong Hwa,Kopyltsov Evgeny,Almagro Elena,Domenech Monserrat,Chang Yen-Hwa,Sautois Brieuc,Ravaux Andre,Aravantinos Gerasimos,Georgoulias Vasileios,Mulder Sasja,Kim Yu Jung,Kater Fabio,Chevreau Christine,Tagawa Scott,Zalewski Pawel,Joly Florence,Loriot Yohann,Hatiboglu Gencay,Gianni Luca,Morelli Franco,Tambaro Rosa,Hashimoto Yasuhiro,Nosov Alexander,Font Albert,Rodriguez-Vida Alejo M.,Jones Robert,Vasudev Naveen,Srinivas Sandhya,Zhang Jingsong,Gil Thierry,Finch Daygen,Grimm Marc-Oliver,Su Yu-Li,Chowdhury Simon,Hocking Christopher,Plas Eugen,North Scott,Jensen Niels Viggo,Theodore Christine,Imkamp Florian,Peer Avivit,Kobayashi Takashi,Sakai Hideki,Sassa Naoto,Yoshimura Kazuhiro,Aarts Maureen,Ferreira Castro Ana,Topuzov Marlen,Rodriguez Juan Francisco,Vazquez Federico Jose,Tsai Yu-Chieh,Crabb Simon,Hussain Syed,Bendell Johanna,Gross-Goupil Marine,Gwenaelle Gravis,Berger Raanan,Statsenko Galina,Evans Linda,Drakaki Alexandra,Somer Bradley,Davis Ian,Lynam James,Borges Giuliano,Dettino Aldo,Fay André P.,Martins Graziella,Zucca Luis Eduardo,Agerbaek Mads,Kalofonos Haralambos,Rosenbaum Eli,Enokida Hideki,Kikukawa Hiroaki,Nishimura Kazuo,Tamada Satoshi,Uemura Motohide,Lopez Yamil,Gietema Jourik,Slojewski Marcin,Fernandes Isabel,Smolin Alexey,Mazhar Danish,Kalebasty Arash Rezazadeh,Carthon Bradley,Loidl Wolfgang,Franke Fabio,Girotto Gustavo,Alimohamed Nimira,Macfarlane Robyn,Pappot Helle,Niegisch Guenter,Mavroudis Dimitrios,Sella Avishay,Porta Camillo,Ebara Shin,Nakamura Motonobu,Obara Wataru,Okuno Norihiko,Shinohara Nobuo,Sugimoto Mikio,Suzuki Akitaka,Tokuda Noriaki,Uemura Hiroji,Yamaguchi Akito,Ramirez Francisco,Rozanowski Pawel,Wiechno Pawel,Keam Bhumsuk,Kislov Nikolay,Plaksin Denis,Cicin Irfan,Kumar Satish,Galsky Matthew D.,Petrylak Daniel P.,Rosales Joseph,Vaishampayan Ulka,Culine Stephane,Papandreou Christos,Nara Taketoshi,Erman Mustafa,Kreiger Laurence,Janoski Juliana,Rosa Diogo,Siqueira Mariana,Canil Christina,Sengelov Lisa,Tourani Jean-Marc,Arai Gaku,Hashine Katsuyoshi,Kawakita Mutsushi,Nakaigawa Noboru,Nomi Hayahito,Shiina Hiroaki,Suzuki Hiroyoshi,Yonese Junji,Kuri Roberto,Macedo Eleazar,Rivera Samuel,Villalobos Prieto Alberto,Polakiewicz-Gilowska Anna,Zaucha Renata,Lopes Fabio,Ponomarev Roman,Pomerantz Mark,Shariat Shahrokh,Luk Cynthia,Lesniewski-Kmak Krzysztof

Funder

AstraZeneca

Publisher

Elsevier BV

Subject

Oncology

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