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3. In the presence of 0.0001% of 1, the production of cathepsin D was increased to 4.8 times that of the control. The biological activities will be reported elsewhere in detail by: Takema, Y.; Kitahara, T.; Higuchi, K. and Ishikawa, J.
4. Horikawa, T.; Mimaki, Y.; Kameyama, A.; Sashida, Y.; Nikaido, T.; Ohmoto, T. Chem. Lett. 1994, 2303. Natural aculeoside A: [α]D −50.0° (c 0.10, MeOH).
5. Absolute configuration of 2,3-dihydroxy-3-methylpentanoic acid, an intermediate in the biosynthesis of isoleucine, and its identity with the esterifying acid of the pyrrolizidine alkaloid strigosine