Leflunomide ameliorates experimental autoimmune myasthenia gravis by regulating humoral and cellular immune responses

Author:

Huang Huan,Ran Hao,Liu Xiaoxi,Yu Lu,Qiu Li,Lin Zhongqiang,Ou Changyi,Lu Yaru,Yang Wenhao,Liu Weibin

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference71 articles.

1. Myasthenia gravis;Gilhus;Nat. Rev. Dis. Primers,2019

2. Pathophysiology and immunological profile of myasthenia gravis and its subgroups;Romi;Curr. Opin. Immunol.,2017

3. Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs;Lennon;J. Exp. Med.,1975

4. F. Baggi, A. Annoni, F. Ubiali, M. Milani, R. Longhi, W. Scaioli, et al., Breakdown of tolerance to a self-peptide of acetylcholine receptor alpha-subunit induces experimental myasthenia gravis in rats, J. Immunol. (Baltimore, Md : 1950). 172(4) (2004) 2697–2703.

5. Experimental Autoimmune Myasthenia Gravis (EAMG): from immunochemical characterization to therapeutic approaches;Fuchs;J. Autoimmun.,2014

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